Dr. Fejzo Makes the Cover of The New York Times

Her doctor said her illness was all in her head. Dr. Fejzo was determined to find the truth. And she did: HG’s most likely genetic cause is GDF15. Read her story in The New York Times.

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2023 HG Challenge

We invite our community to take Provider Packets of resources to a hospital, clinic, or practice with your personal story and passion will make a difference.

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Highlights of SMFM 2023

Overall, this study contributes to our understanding of the biology of nausea and vomiting in pregnancy and may lead to future research evaluating new treatment avenues. Of note, drugs targeting the GDF15 pathway have shown great promise in mitigating weight loss, loss of appetite, and vomiting in animal models and are currently in clinical trials in cancer cachexia, a disease with similar symptoms to HG.

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Heart Health and Hyperemesis Gravidarum

February is Heart Health Month, and the HER Foundation shares 4 ways for you to protect your heart. 

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HG Reality 2023

May 15th is International HG Awareness Day, and the international HG community has chosen the theme: HG Reality. You can help the HER Foundation raise awareness and educate about your HG Reality!

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Keystone Conference

Dr. Marlena Fejzo, HER Research Adviser and Board of Directors, was invited to speak at February’s Keystone Conference on Maternal-Fetal Crosstalk in Santa Fe, NM. Dr. Fejzo presented “Evidence the placenta and appetite hormone GDF15 causes nausea and vomiting of pregnancy” and met with experts on maternal/fetal health from around the world. 

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HER Research Surveys

Be a part of finding answers about Hyperemesis Gravidarum (HG). Currently, the HER Foundation has three active research surveys. Please participate!

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Impact Report: 2021-2022

The HER Foundation is excited to share our Impact Report with highlights of 2021 and 2022. We are Helping Generations across the globe! The HER Foundation is the only dedicated HG research team in the world doing genetics research on Hyperemesis Gravidarum and is the only voice of advocacy for HG in the US and in many other countries!

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Best of 2022

The HER Foundation has accomplished a lot in 2022! We are thankful for the support of our donors and community and want to share the highlights that made this HER’s best year yet! This is what 22 years of Helping Generations survive Hyperemesis Gravidarum (HG) looks like.

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newborn

Queeneth Shares a Beautiful Message of Thanks

We are glad to inform you of the arrival of our son. He was born weighing 7 pounds and 3 ounces. While we are most grateful to God, we are particularly very thankful and appreciative of all of the support the HER Foundation gave us. 

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Tala Shares #HERstory

The HER Foundation educated me on the website and social media, and I used the HG Care app. When I was scared to take Zofran, they sent me the lastest research. HER understands, and I didn’t feel alone. One day, they will find a cure.

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Candace Renee and Maxwell on HG and Prematurity

Candace Renee, Maxwell’s mom, TV Personality, Actress, and Host and star on Floribama Shore talks with HER about Hyperemesis Gravidarum (HG) and her son’s premature birth.

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Our NEW Patient Treatment Overview

What is hyperemesis gravidarum and how is it treated? How do you treat hyperemesis gravidarum in the first trimester? When will hyperemesis gravidarum end? Who is at risk for hyperemesis gravidarum?

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Enteral Nutrition

What is the best treatment for hyperemesis gravidarum (HG)?

What is the best treatment for hyperemesis gravidarum? What is the cause of hyperemesis gravidarum?
What is hyperemesis gravidarum and how is it treated? Is hyperemesis a high risk pregnancy? How do you relieve hyperemesis gravidarum?

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Why is thiamin (B1) important for HG patients?

Thiamin (or thiamine) is another name for vitamin B1. It is a water-soluble, nontoxic B vitamin that is depleted within 2 weeks of not eating normally. Potentially life-threatening complications can develop for mom and baby if depleted.

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Amy Schumer Joins HER’s Board of Directors

The HER Foundation is thrilled to announce that Emmy-winning and Golden Globe-nominated standup comedian, actress, writer, producer, and director Amy Schumer will join the HER Foundation’s Board of Directors. 

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BJOG publishes HER/USC study on the genetics of HG

The HER Foundation continues the breakthroughs with publication of “Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum” in BJOG.

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Aijia Grammer in hospital bed for treatment

What is HG?

Hyperemesis gravidarum (HG) does not look the same for every patient. Learn about the severity levels.

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Dr. Fejzo is featured in Inverse

Dr. Marlena Fejzo, geneticist and HER’s Research Advisor and member of the Board of Directors, was featured in the Inverse article, “When morning sickness kills: doctors have dismissed hyperemesis gravidarum for decades, but new research could undo this harmful legacy.”

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Complications Secondary to Hyperemesis Gravidarum

Hyperemesis Gravidarum (HG) is not self-limiting, and its impact can last a lifetime for mothers and their children. Until there is recognition of this fact and comprehensive, universal, effective treatment for all HG patients, every level of society will continue to face the costs of HG.

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Levels of Medication for Hyperemesis Gravidarum

Individual response to Hyperemesis Gravidarum (HG) medication varies due to many factors including genetics and hydration. If a patient is vomiting constantly, oral dosing of medications will likely be ineffective and alternates such as sublingual, transdermal (patch/cream), subcutaneous (subQ), intravenous (IV), or other routes should be considered along with hydration.

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Nausea Strategies

While some medications target vomiting (ondansetron/Zofran), there are no medications that specifically target nausea. Some medications used to treat Hyperemesis Gravidarum (HG) may help reduce nausea but rarely will medications eliminate all nausea. Since there are numerous causes of nausea, treating as many as possible is most effective. This list of strategies may help reduce nausea depending on what is triggering symptoms. None works for everyone, but each may help a little.

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Why we do what we do!

The HER Foundation’s staff, clinicians and referral coordinator volunteer many hours each year to respond to thousands of emails, messages, and calls for help with Hyperemesis Gravidarum (HG). This is core to our mission, and we want to share why we want to expand this service. Enjoy these heartwarming messages and stories.

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HER Psychosocial Research

The HER Foundation’s breakthrough psychosocial study shows that Hyperemesis Gravidarum (HG) is not self limiting and has societal implications.

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mom and meds

Research Summary: Safety of Ondansetron (Zofran) in Pregnancy

Read the latest research on the safety of ondansetron (Zofran) in an HG pregnancy.

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How to Support an Employee with HG or other High Risk Complications of Pregnancy

Dozens of mothers bravely raised their voices about the obstacles that prohibited them from being healthy, productive employees during their pregnancies, including insufficient job security and a lack of compassion from employers. We compiled their responses to make a succinct list employers can refer to when attempting to support employees with HG or other high risk pregnancy complications. 

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Dr. Fejzo speaks at the Fetal Medicine Foundation

Dr. Marlena Fejzo, a geneticist at the University of Southern California and a HER Foundation Board of Directors, presented at the Fetal Medicine Foundation (FMF) about Hyperemesis Gravidarum (HG), its potential causes, and treatment options. Over 5600 medical professionals heard her speak, and the talk is freely available on the FMF’s website in English, Spanish, Russian, and Portuguese.

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Help Eliminate Preventable Complications of HG

The devastating complications of HG are numerous, the silver lining is that a great many of them are preventable with timely, effective, adequate medical care. To this end, the HER Foundation launched the 1 MOM Is 2 Many campaign.

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The vomiting won’t stop. When to call a health professional.

When do HG patients call their doctor? When do I go to the hospital with hyperesis gravidarum?

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Do I need fluids? Am I dehydrated?

When do I go to the hospital with hyperemesis gravidarum? When do I need fluids with HG? What are the best treatments for hyperemesis gravidarum?

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Hannah’s #HGreality

I knew nearly nothing about hyperemesis, even after my ER diagnosis. The HER website helped educate me about symptoms and how to approach medical professionals. HER helped alleviate some concerns about medications.

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AmazonSmile charitable giving program ends

Amazon’s charitable giving based on your shopping is ending. We rely on those donations for ~$2600 in operating costs covering site fees for about 10 months of the year. Please help us meet this deficit by giving today, creating a monthly donation, or hosting a fundraiser? Our resources and support are free to all in need because of those who gave in the past. Will you help those who come after you? Please give today!

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ICHG 2024

Join us November 6-7, 2024 in Ventura, California (near LA), for two days of engaging with top scientists and clinicians specializing in HG management.

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