A new study published in Nature reveals abnormally high levels of the hormone GDF15, and increased sensitivity to it, are the major factors contributing to HG. The most severe form…
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Be a part of finding answers about Hyperemesis Gravidarum (HG). Currently, the HER Foundation has three active research surveys. Please participate!
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HER’s Dr. Marlena Fejzo was invited to speak at Fortune’s Most Powerful Women Next Gen which brings together leaders of tomorrow’s Fortune 500 companies, rising executives from the nations’s biggest…
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Using genetics, the HER Foundation, led by Marlena Fejzo, PhD., found the cause of HG is related to the nausea and vomiting hormone GDF15. Our newest study is pending publication and was featured in New Scientist.
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HER’s HG experts answer common questions Do you want to learn more about hyperemesis gravidarum (HG)? HER’s HG experts are here to clarify the conversation surrounding hyperemesis and clear up misconceptions. How…
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The Zeta Omega Eta sorority of the University of Michigan recently hosted a sticker sale on campus to benefit the HER Foundation, and the fundraiser was a huge success!
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Her doctor said her illness was all in her head. Dr. Fejzo was determined to find the truth. And she did: HG’s most likely genetic cause is GDF15. Read her story in The New York Times.
Read MoreApril 2, 2022, is World Autism Awareness Day. At the HER Foundation, we light up kindness and wear blue in support of understanding and acceptance for people with autism. Children born after an HG pregnancy have an increased risk of an autism diagnosis, and we are grateful for each of these children.
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Overall, this study contributes to our understanding of the biology of nausea and vomiting in pregnancy and may lead to future research evaluating new treatment avenues. Of note, drugs targeting the GDF15 pathway have shown great promise in mitigating weight loss, loss of appetite, and vomiting in animal models and are currently in clinical trials in cancer cachexia, a disease with similar symptoms to HG.
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Hyperemesis Gravidarum (HG) is not self-limiting, and its impact can last a lifetime for mothers and their children. Until there is recognition of this fact and comprehensive, universal, effective treatment for all HG patients, every level of society will continue to face the costs of HG.
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