Our Collaborative Studies: HG Genetics Research
- GF(opens in new tab)RAL genetic variations and circulating GFRAL in(opens in new tab) hyperemesis gravidarum -- iScience, A Cell Press Journal, 2026
- Prepregnancy metformin use associated with lower risk of severe nausea and vomiting of pregnancy and hyperemesis gravidarum(opens in new tab) -- Am J of Ob Gyn, 2025
- Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes(opens in new tab) -- Trends in Molecular Medicine, 2024
- GDF15 linked to maternal risk of nausea and vomiting during pregnancy(opens in new tab) -- Nature Journal, 2023
- Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum(opens in new tab), BJOG, 2022.
- Abstract: Additional risk variant in GDF15 and a stronger maternal genetic influence linked to Hyperemesis Gravidarum(opens in new tab)
--AJOG, 2020. ACOG POSTER (opens in new tab) - Hormone receptor genes PGR and GFRAL linked to hyperemesis gravidarum
(opens in new tab)--AJOG, 2019. - Analysis of GDF15 and IGFBP7 in Hyperemesis Gravidarum Support Causality
(opens in new tab)--Geburtsh Frauenheilk, 2019. - Evidence GDF15 Plays a Role in Familial and Recurrent HG
(opens in new tab)--Geburtsh Frauenheilk, 2018. - Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum
(opens in new tab)--Nature Communications, 2018. - Genetic analysis of hyperemesis gravidarum reveals association with
intracellular calcium release channel (RYR2)
(opens in new tab)--Molecular and Cellular Endocrinology, 2016. - Hyperemesis gravidarum: it is time to put an end to the misguided theory of a psychiatric etiology
(opens in new tab)-- SciVerse ScienceDirect, 2012 - Familial aggregation of hyperemesis gravidarum(opens in new tab).
-- AJOG, 2010. - High prevalence of severe nausea and vomiting of pregnancy and hyperemesis gravidarum among relatives of affected individuals.
-- Eur J Obstet Gynecol Reprod Biol., 2008
Presentations
- ICHG 2017 Dr. Fejzo presents first findings(opens in new tab) on GDF15
HER Foundation Research
Although hyperemesis gravidarum (HG) affects at least 6 million pregnancies annually across the globe, the interest and funding for HG research is very small. HER has been collaborating with the world's leading researcher, Dr. Marlena Fejzo since 2001 and received only community and private funding for many studies. We collaborate with experts from universities beyond the US and are the leading research team for HG with many groundbreaking studies including finding the first causes of HG, your genes!
First we found the gene,
Then we found the mutation,
Now we found the mechanism,
Help us find the cure!
Donate to HER.
Together, we can make HG history!
