This is not morning sickness.

1 in 3 HG pregnancies ends in loss, mothers still die in the 21st Century.

Woman with feeding tube
HG baby
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Maternal Complications Due to Hyperemesis

Hyperemesis Gravidarum (HG) increases maternal risk of malnutrition, Wernicke's encephalopathy (WE), sepsis, thiamin deficiency (TD), preeclampsia, hemorrhage, preterm labor, post traumatic stress disorder (PTSD), Perinatal Mood and Anxiety Disorders (PMAD), embolism, peripartum cardiomyopathy (PPCM), and placental abruption.

Malnutrition

Acute malnutrition due to lack of macronutrients and micronutrients causes weight loss, muscle wasting, immobility, and other serious complications and may be fatal for both mother and child.

Wernicke's Encephalopathy

Wernicke's encephalopathy is a neurological emergency caused by vitamin B1 deficiencies that must be treated immediately to prevent serious or fatal complications for both mother and child.

Sepsis

According to the CDC, 12.5% of maternal deaths between 2011-2016 were caused by infection or sepsis. HG puts women at higher risk due to reduced immune function, invasive procedures, and urinary tract infections.

Thiamin Deficiency

Vitamin B1 comes from food and supplements, but is depleted within two weeks of HG, leading to complications which initially share the symptoms of HG and worsen HG but may become life-threatening. Know the signs: changes in vision, speech, gait/movement, cognition, cardiac function, and mood.

Women with prolonged HG are twice as likely to develop preeclampsia and more likely to experience eclamptic seizures possibly due to malnutrition, stress, immune dysfunction, hormone and neurotransmitter changes, kidney dysfunction, premature birth, and fetal demise.

Hemorrhage

The risk of hemorrhage is greater in HG due to malnutrition and the changes of pregnancy, plus complications of HG including placental abruption and preeclampsia.

Preterm Labor

Women with HG have 2x the risk of preterm labor, a 4-fold increased risk of premature birth, and are more likely to deliver babies that are small for gestational age and growth restricted likely due to malnutrition and stress.

PTSD

18% of women with HG meet full criteria PTSD compared to 9% of all pregnant women, and about half of HG survivors have symptoms of trauma due to severe nausea/vomiting, fear of loss, complications, and invasive procedures.

PMADs

1 in 3 women with HG are diagnosed with Perinatal Mood and Anxiety Disorders compared to 1 in 7 of all pregnant women. The risk increases with severe and prolonged HG symptoms which increase physical and psychosocial challenges.

Embolism

The risk of clotting or embolism increases due to pregnancy and is exacerbated by dehydration, malnutrition, and immobility due to HG. Pulmonary embolism is the leading cause of death in pregnancy.

PPCM

Peripartum cardiomyopathy, which can be life-threatening, may occur due to malnutrition in HG and presents as shortness of breath, swelling, rapid weight gain, irregular heartbeat, and chest pain.

Placental Abruption

Women with HG extending beyond the 1st trimester are 3x more likely to have placental abruptions which can lead to life-threatening hemorrhage, preterm delivery, hypoxic encephalopathy and fetal demise.

Fetal Complications

Hyperemesis Gravidarum (HG) increases fetal risk of Intrauterine Growth Restriction or Small for Gestational Age (IUGR/SGA), prematurity, neurodevelopmental issues, autism spectrum disorder, speech and language delay, Sensory Processing Disorder, learning disabilities, adult mental health issues, and adult cardiometabolic issues. 1 in 3 babies does not make it to term.

IUGR/SGA

Intrauterine Growth Restriction or Small for Gestational Age is more commonly diagnosed in babies exposed to HG due to malnutrition.

Prematurity

Babies exposed to HG are too often born early as HG is a leading cause of premature labor and delivery likely due to chronic and prolonged malnutrition and dehydration in the mother.

Neurological Impact

Children exposed to HG in utero have a 3.3-fold increase in neurodevelopmental issues with the risk increasing as mothers' symptoms are prolonged and weight loss increases.

Autism Spectrum

Autism spectrum disorders have been found to occur more frequently in children born to mothers who had hyperemesis gravidarum, most likely due to stress, malnutrition, and other factors.

Language Delays

Speech and language delays are more common in children of HG mothers with the risk being greatest in those born to mothers with severe or prolonged symptoms.

Sensory Processing

Many experiencing severe or prolonged HG, especially those on bed rest late in pregnancy, have children with Sensory Processing Disorder likely due to stress, an immature vestibular system, and malnutrition.

Learning Disabilities

Delays in learning are more common in children of HG mothers with the risk being greatest in those born to mothers with severe or prolonged symptoms.

Mental Health 

Children exposure to HG in utero have a 3.6-fold increased risk (38% vs 15% controls) of childhood conduct issues, and doubles the risk of adult mental health disorders, primarily depression, bipolar disorder, and anxiety.

Adult Cardiometabolic

A significant number of those exposed to HG in utero will develop chronic cardiac and metabolic issues in adulthood. Findings on this vary.

Symptoms MS v. HG (1)-min

01

EDUCATE

Learn the risks and complications of HG and how comprehensive, universal  assessment and treatment can improve outcomes.

02

AMPLIFY

Amplify the message that 1 MOM is 2 Many to suffer preventable complications and loss due to HG.

03

ADVOCATE

Advocate for state and federal policies that work to eradicate preventable maternal and fetal mortality and morbidity due to HG.