Research on HG's short- and long-term effects is desperately needed and needed now. We need to do more to find a cure for this disease that has such devastating effects on a growing number of soon-to-be mothers.
Congressman Xavier Becerra (CA)
HG forces women to make difficult decisions... the H.E.R. web site is the most comprehensice location to educatte oneself to make the best decisions.
Marlena S. Fejzo, PhD USA
HG is a devastating illness and yet so little research has been undertaken into causes and therapies.
Dr. Matthes Seeling, MD
HG is a termendously debilitating disease that can have life long consequences. This Web site will provide much needed support to mothers suffering from this disease.
TM Goodwin, MD USA
HG has a devastating personal and family impact and effective management is most important.
Ron Taylor, MD UK
Take a Survey

If you had hyperemesis gravidarum (HG), did you need multiple dental repairs or reconstruction, or experience significant problems with your jaw, mouth or neck function as a result of HG? (e.g. cavities, root canal, TMJ, disc herniation, etc.)

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Related Links

Current Research Surveys

HER Foundation and University of Southern California Collaboration

Current 2007-2012 Study: Genetics of Hyperemesis Gravidarum (HG)

HG Researchers need your help! This study is designed to identify individuals affected with HG, to study epidemiologic factors via an online survey, to collect DNA samples from saliva through the mail at no cost or travel for you, and to search for genes and risk factors that may be potentially associated with this condition. To be eligible, you must have suffered from HG and had treatment for your HG that includes i.v. hydration, TPN or other form of non-oral feeding (ie nasogastric feeding), OR both, and are able to recruit a friend with at least 2 pregnancies who has NOT suffered from HG to serve as a control. If you live in the United States and are interested, please contact Marlena Schoenberg Fejzo, PhD at or 310-210-0802. Download the USC Consent Form (804 Kb PDF) for more details about the study.

Once you have a study ID number, you can begin your survey at this link: http://www.helpher.org/HER-Research/2007-Genetics/

Identification of genes and risk factors that contribute to HG will lead to a better understanding of the causes of severe nausea and vomiting of pregnancy, and should be a first step toward the development of more effective treatments or a cure for this devastating disease. To learn more about why Marlena is devoted to finding the cause of HG and information about participating in the study watch Marlena's youtube.com video here.External Link

Other HER Foundation Surveys and Polls

Although hyperemesis gravidarum (HG) affects thousands of women annually, few research studies are published annually in comparison to other disorders. We collaborate with experts on research related to HG, as well as conduct semi-annual, online surveys and polls to further our understanding of HG and its treatment. Our Internet research allows us to capture data from around the globe on much larger numbers of participants. Most studies done on HG have less than 200 participants, are not controlled or randomized, and/or may not have enough evidence to support conclusions. Our studies often have over 1000 participants with HG, and we are able work with international experts on HG.

In short, too often HG studies do not meet current research standards. Thus, we aim to conduct and fund research that accurately defines the incidence, outcomes and proactive management of HG to help women get the care they and their unborn child need to survive. We accept donations to sponsor research grants.

 

Other HG Research Opportunities

Motherisk

Motherisk conducts studies to investigate the safety and efficacy of medications during pregnancy. If you are currently pregnant and would like to participate in their studies, see their website or call their toll free NVP Helpline at 1-800-436-8477 to enroll in a study. Participation usually involves brief phone interviews, that are strictly confidential. Review Motherisk's Current Studies

Governmental Studies (US)

Pregnancy Registry (FDA/Office of Women's Health) If you are pregnant and currently taking medicine — or have been exposed to a medicine during your pregnancy — you may be able to participate and help in the collection of needed information. This web site provides a list of pregnancy registries that are seeking participants.

ClinicalTrials.gov is a service of the National Institutes of Health Developed by the National Library of Medicine. You can search for research studies in which to participate as well as investigate the findings of medical research.

Updated on: Apr. 19, 2010

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